Biomolecular Display Technologies | 36.69 MB
Title: Biomolecular Display Technologies
Author: Huan Peng, Theam Soon Lim
Category: Nonfiction, Science & Nature, Science, Biological Sciences, Biochemistry, Health & Well Being, Medical, Reference, Research, Medical Science, Pharmacology
Language: English | 313 Pages | ISBN: 9781071652497
Description:
This volume explores major biomolecular display platforms and their applications, which allow researchers to mine vast, diverse libraries for functional variants, bridging molecular design and real-world application. Beginning with a section on foundational techniques for functional libraries, the book continues by covering tailored yeast, phage, and cDNA display strategies to boost efficiency, modulate binding, and engineer scaffolds for specialized needs, display-driven identification of macrocyclic ligands, nanoparticle-binding peptides, epitopes, and functional proteins, as well as computational advances, protein engineering, and post-selection analysis to refine hits and accelerate translation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Authoritative and practical, Biomolecular Display Technologies offers expert guidance and insight into the transformative potential of display technologies.
This volume explores major biomolecular display platforms and their applications, which allow researchers to mine vast, diverse libraries for functional variants, bridging molecular design and real-world application. Beginning with a section on foundational techniques for functional libraries, the book continues by covering tailored yeast, phage, and cDNA display strategies to boost efficiency, modulate binding, and engineer scaffolds for specialized needs, display-driven identification of macrocyclic ligands, nanoparticle-binding peptides, epitopes, and functional proteins, as well as computational advances, protein engineering, and post-selection analysis to refine hits and accelerate translation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Authoritative and practical, Biomolecular Display Technologies offers expert guidance and insight into the transformative potential of display technologies.
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