Cancer Metabolism Molecular Mechanisms and Therapeutic Strategies | 15.35 MB
Title: Cancer Treatment and Research
Author: Unbekannt
Category: Nonfiction, Health & Well Being, Medical, Specialties, Oncology
Language: English | 282 Pages | ISBN: 3319536575
Description:
Cancer cells survive and thrive by radically reshaping the way they use energy, nutrients, and metabolic pathways. This book offers a clear and comprehensive exploration of this rapidly evolving field, revealing how tumors rewire core biochemical processes to sustain proliferation, evade cell death, and adapt to the pressures of the tumor microenvironment. From foundational concepts to cutting‑edge discoveries, the book provides an essential entry point for understanding the metabolic logic that underlies cancer progression.
Central to this volume is an in‑depth examination of glutamine metabolism. Alongside this focus, the book extends broadly across the metabolic landscape, covering glycolysis, lipid synthesis and utilization, redox regulation, mitochondrial dynamics, and metabolic communication between cancer cells and their surrounding stromal and immune partners. Each chapter distills mechanistic insight while emphasizing translational relevance, bridging basic science with the latest therapeutic strategies and clinical applications.
Written by leading researchers and clinicians, this book serves as a valuable resource for scientists, oncologists, and drug developers seeking to understand and target the metabolic vulnerabilities of cancer. Whether exploring metabolic reprogramming in cancer stem cells, evaluating biomarkers of metabolic states, or assessing emerging therapies and clinical trial data, readers will gain an integrated perspective on how metabolism shapes tumor behavior and influences treatment outcomes. This is an indispensable guide for anyone committed to advancing cancer research, improving patient care, and translating metabolic insights into meaningful therapeutic advances.
Cancer cells survive and thrive by radically reshaping the way they use energy, nutrients, and metabolic pathways. This book offers a clear and comprehensive exploration of this rapidly evolving field, revealing how tumors rewire core biochemical processes to sustain proliferation, evade cell death, and adapt to the pressures of the tumor microenvironment. From foundational concepts to cutting‑edge discoveries, the book provides an essential entry point for understanding the metabolic logic that underlies cancer progression.
Central to this volume is an in‑depth examination of glutamine metabolism. Alongside this focus, the book extends broadly across the metabolic landscape, covering glycolysis, lipid synthesis and utilization, redox regulation, mitochondrial dynamics, and metabolic communication between cancer cells and their surrounding stromal and immune partners. Each chapter distills mechanistic insight while emphasizing translational relevance, bridging basic science with the latest therapeutic strategies and clinical applications.
Written by leading researchers and clinicians, this book serves as a valuable resource for scientists, oncologists, and drug developers seeking to understand and target the metabolic vulnerabilities of cancer. Whether exploring metabolic reprogramming in cancer stem cells, evaluating biomarkers of metabolic states, or assessing emerging therapies and clinical trial data, readers will gain an integrated perspective on how metabolism shapes tumor behavior and influences treatment outcomes. This is an indispensable guide for anyone committed to advancing cancer research, improving patient care, and translating metabolic insights into meaningful therapeutic advances.
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